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2023

5

WGA-M001, a Mixture of Total Extracts of Tagetes erecta and Ocimum basilicum, Synergistically Alleviates Cartilage Destruction by Inhibiting ERK and NF-¥êB Signaling. International Journal of Molecular Sciences. (IF : 6.208) 2023

4

Novel molecule BBC0901 inhibits BRD4 and acts as a catabolic regulator in the pathogenesis of osteoarthritis.  Biomedicine & Pharmacotherapy (IF : 7.419). 2023

3 Schisandra extract ameliorates arthritis pathogenesis by suppressing the NF-¥êB and MAPK signalling pathways.   J Cell Mol Med (IF : 5.31). 2023
2 Prussian blue nanozymes coated with pluronic attenuate inflammatory osteoarthritis by blocking c-Jun N-terminal kinase phosphorylation. Biomaterials (IF : 15.304). 2023
1

Blockade of Activin Receptor IIB Protects Arthritis Pathogenesis by Non-Amplification of Activin A-ACVR2B-NOX4 Axis Pathway. Advanced Science (IF : 17.521)2023

2022

2

FructoseDerived Levan Nanoparticles Protect Against Osteoarthritis by Directly Blocking CD44 Activation. 

Small (IF : 15.153) 2022 

1

Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance. Science Advances (IF : 14.136) 2022

2021

4
Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model. International Journal of Molecular Sciences (IF : 6.208) 2021
3

Safflower Seed Extract Attenuates the Development of Osteoarthritis by Blocking NF-¥êB

Signaling. Pharmaceuticals (IF : 5.215) 2021

2

Self-assembled hyaluronic acid nanoparticles for osteoarthritis treatment. Biomaterials (IF : 15.304) 2021

1 Obtusifolin, an Anthraquinone Extracted from Senna obtusifolia (L.) H.S.Irwin & Barneby, Reduces Inflammation in a Mouse Osteoarthritis Model. Pharmaceuticals (IF : 5.215) 2021

2020

3

3¡Ç-Sialyllactose prebiotics prevents skin inflammation via regulatory T cell differentiation in atopic dermatitis mouse models. Scientific reports (IF : 4.997) 2020

2

TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis. 

Annals of the Rheumatic Diseases (IF : 28.003) 2020

1

Seomae mugwort and jaceosidin attenuate osteoarthritic cartilage damage by blocking I¥êB degradation in mice.  

J Cell Mol Med (IF : 5.295) 2020

2019

1

Cirsium japonicum var. maackii and apigenin block Hif2¥áinduced osteoarthritic cartilage destruction. 

J Cell Mol Med (IF : 5.295)  2019

2018

3

ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis.

Science Translational Medicine (IF : 19.343) 2018

2

3'-Sialyllactos as an inhibitor of p65 phosphorylation ameliorates the progression of experimental rheumatoid arthritis.  British Journal of Pharmacology (IF : 9.473). 2018 

1

Self-assembled hyaluronic acid nanoparticles: Implications as a nanomedicine for treatment of type 2 diabetes. 

J Control Release (IF : 11.467). 2018

2017

2

Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells.

J Cell Mol Med (IF : 5.295) 2017

1

3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis.

J Cell Mol Med (IF : 5.295). 2017

2016

2 Autologous bone marrow mesenchymal cell induced chondrogenesis for the treatment of osteoarthritis of knee. Tissue Engineering and Regenerative Medicine (IF : 4.323) 2016
1 Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer. Oncotarget (IF : 0.966). 2016

2015

4

Yang et al., Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.

Science (IF : 63.832) 2015 

3 Yang et al., NAMPT (visfatin), a direct target of hypoxia-inducible factor-2a, is an essential catabolic regulator of osteoarthritis. Annals of the Rheumatic Diseases (IF : 28.003)  2015 
2

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.

Blood (IF : 25.669) 2015

1 Reciprocal regulation by hypoxia-inducible factor-2a and the NAMPT-NAD+-SIRT axis in articular chondrocytes in involved in osteoarthritis. Osteoarthritis and Cartilage (IF : 7.507) 2015

2013

1

Yang et al., Aire¡¯s plant homeodomain(PHD)-2 is critical for induction of immunological tolerance.

Proc Natl Acad Sci U S A (IF : 12.779). 2013 

2012

2 Misexpression of Dickkopf-1 in endothelial cells, but not in chondrocytes or hypertrophic chondrocytes, causes defects in endochondral ossification. J Bone Miner Res (IF : 6.39). 2012
1

Hypoxia-inducible factor-2¥á regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction. Cell Death Differ (IF : 12.073) . 2012 

2011

1 Interleukin-6 plays an essential role in hypoxia-inducible factor-2a-induced experimental osteoarthritic cartilage destruction in mice. Arthritis Rheum (IF : 15.483) . 2011 Sep;63(9):2732-43

2010

1

Yang et al., Hypoxia-inducible factor-2a is a catabolic regulator of osteoarthritic cartilage destruction. 

Nature Medicine (IF : 87.241). 2010 

~ 2009

5

Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction. Gene. 2009

4

Matrix metalloproteinase (MMP)-12 regulates MMP-9 expression in interleukin-1beta-treated articular chondrocytes. J Cell Biochem. 2008

3 Wnt signaling in cartilage development and degeneration. BMB Rep. 2008
2

Enhanced expression of human cytochrome P450 1A2 by co-expression with human molecular chaperone Hsp70. 

Toxicol Lett. 2004

1

High-level expression of human cytochrome P450 1A2 by co-expression with human molecular chaperone HDJ-1(Hsp40). Protein Expr Purif. 2004